Extended Data Fig. 1: Replication failure rates at different PIP thresholds.
From: Improving fine-mapping by modeling infinitesimal effects
Replication failure rates at four different PIP thresholds: 0.9 (default), 0.93, 0.95, 0.99, for SuSiE, FINEMAP, SuSiE-inf, and FINEMAP-inf aggregated across 10 UKBB quantitative phenotypes, contrasted with RFRs in ideal simulations and with EPN. Error bars represent one SD of the corresponding binomial distribution Binom(n, p), where n is the total number of high-PIP variants at sample size N = 100 K, and p is the RFR. Bar plot data is presented as RFR + /- SD. Numerical results are available in Supplementary Table 14.
