Extended Data Fig. 6: Relative prediction accuracy of different methods to SBayesR for 50 UKB traits. | Nature Genetics

Extended Data Fig. 6: Relative prediction accuracy of different methods to SBayesR for 50 UKB traits.

From: Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries

Extended Data Fig. 6

Plots shows relative prediction accuracy of different methods to SBayesR using 1 M HapMap3 SNPs, averaged from 10-fold cross-validation for 50 UKB traits. Except for LDpred2 and SBayesR (HapMap3 SNPs without annotation), all other methods used imputed 7 M SNPs with functional annotations. The dashed line indicates the improved prediction accuracy equals to 0 (prediction accuracy equals to SBayesR using 1 M HapMap3 SNPs). Each box plot shows the spread of data in 50 traits; the line is the middle (median), the box covers the middle half (IQR), the whiskers extend to 1.5 times the IQR, and dots show outliers.

Back to article page