Extended Data Fig. 1: Schematic overview of SBayesRC. | Nature Genetics

Extended Data Fig. 1: Schematic overview of SBayesRC.

From: Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries

Extended Data Fig. 1

a, A resource-efficient low-rank model that simultaneously fits sequence-level SNPs with high computation efficiency and has independent residuals. Solid blue box denotes a dense matrix or vector. b, A hierarchical multicomponent mixture prior for SNP effects that incorporates functional annotation data and allows for any distribution of SNP effects in each annotation.

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