Extended Data Fig. 2: Robustness of SBayesRC to the choice of LD reference in simulation with HapMap3 SNP panel. | Nature Genetics

Extended Data Fig. 2: Robustness of SBayesRC to the choice of LD reference in simulation with HapMap3 SNP panel.

From: Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries

Extended Data Fig. 2: Robustness of SBayesRC to the choice of LD reference in simulation with HapMap3 SNP panel.

LD reference datasets included: ukb20k, 20,000 random sample from the UKB of European ancestry (EUR); ukb10k, 10,000 random sample from UKB EUR; ukb4k, 4,000 random sample from UKB EUR; uk10k, 3,642 unrelated samples from the UK10K dataset; ukb0.5k, 500 random sample from UKB EUR; 1kg0.5k, 494 unrelated samples from 1000GP EUR; afr4k, 4,000 random samples from the UKB of African ancestry (AFR). Each box plot shows the spread of data in 10 independent simulations; the line is the middle (median), the box covers the middle half (IQR), the whiskers extend to 1.5 times the IQR, and dots show outliers.

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