Extended Data Fig. 2: Association between the reasons to stop along each phase of the clinical development as reported by ClinicalTrials.gov.
From: Genetic factors associated with reasons for clinical trial stoppage
Underpowered reasons for stoppage were excluded. We used a two-tailed Fisher’s exact test to assess the significance of the associations, with a p-value threshold of 0.05 (n = 10,214 independent stopped trials). Significant associations are highlighted in blue. Error bars represent 95% confidence intervals for the odds ratio. All results are provided in Supplementary Table 6.
