Table 2 Number of unique gene–ICD10 associations (P < 1 × 10−8)

From: Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank

 

Category

Number of unique associations

Number of unique ICD10 codes

Number of unique genes

ICD10 codes collapsed to three-character level

Known binary (with same direction of effect)

236

116

82

ICD10 codes collapsed to three-character level

Known quant

1,047

397

70

ICD10 codes collapsed to three-character level

Putative novel

182

145

57

All ICD10 codes

Known binary (with same direction of effect)

506

293

82

All ICD10 codes

Known quant

2,168

1,057

70

All ICD10 codes

Putative novel

231

200

57

  1. The gene–ICD10 association with the lowest P value across all ten nonsynonymous QV models, three time-models and four augmented cohorts was reported.
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