Fig. 8: A variant map indicates potential second-line therapies.
From: Base editing screens define the genetic landscape of cancer drug resistance mechanisms

A variant function map highlights variants modulating drug sensitivity in cancer cells. Potential alternative treatments tested in this study are listed. Genotypes are from next-generation sequencing or Sanger sequencing of hits from base editing screens. See also Extended Data Fig. 10 and Supplementary Tables 15–17. Created with BioRender.com.