Fig. 8: A variant map indicates potential second-line therapies. | Nature Genetics

Fig. 8: A variant map indicates potential second-line therapies.

From: Base editing screens define the genetic landscape of cancer drug resistance mechanisms

Fig. 8: A variant map indicates potential second-line therapies.

A variant function map highlights variants modulating drug sensitivity in cancer cells. Potential alternative treatments tested in this study are listed. Genotypes are from next-generation sequencing or Sanger sequencing of hits from base editing screens. See also Extended Data Fig. 10 and Supplementary Tables 1517. Created with BioRender.com.

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