Advancements in single-cell analysis technologies are enabling exploration of the intricacies of the human brain at unprecedented resolution. However, most research thus far has focused on the adult brain. Here, these tools are applied to reveal cell-type-specific gene-expression dynamics as the brain grows from childhood to adulthood.
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This is a summary of: Steyn, C. et al. A temporal cortex cell atlas highlights gene expression dynamics during human brain maturation. Nat. Genet. https://doi.org/10.1038/s41588-024-01990-6 (2024).
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Exploring gene expression in the maturing human brain at the single-cell level. Nat Genet 56, 2598–2599 (2024). https://doi.org/10.1038/s41588-024-01991-5
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DOI: https://doi.org/10.1038/s41588-024-01991-5
