Extended Data Fig. 2: Characterization of immunotherapy-treated NSCLC by combined scRNA-seq and spatial transcriptomic analysis.

a, Dot-heat plot showing the marker genes for each T cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. b, Dot-heat plot showing the marker genes for each B cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. c, Dot-heat plot showing the marker genes for each Mono/Macro cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. d, Dot-heat plot showing the marker genes for each CD31− stromal cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. e, Dot-heat plot showing the marker genes for each DC cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. f, Dot-heat plot showing the marker genes for each endothelial cluster. The color gradient represents the scaled expression level, and the diameter represents the percentage of cells. Related to Fig. 1.