Extended Data Fig. 5: Percentage of carriers among cases stratified by age at AF diagnosis including rare coding and structural variants among WGS samples. | Nature Genetics

Extended Data Fig. 5: Percentage of carriers among cases stratified by age at AF diagnosis including rare coding and structural variants among WGS samples.

From: Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Extended Data Fig. 5

Each square represents the percentage of carriers among AF cases across within samples with WGS from TOPMed-CCDG. The age at AF diagnosis was stratified by ≤35, ≤45, ≤55, ≤65, and any. The numbers at the bottom describe the total number of carriers and the total number of cases from AF cases whose age at AF diagnosis are available. The center measures represent proportions, while the error bars represent 95% binomial confidence intervals. TTNpsi90%: variants located at exons with percent spliced-in index > 90% for TTN within left ventricular tissue.

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