Fig. 2: ImmuneLENS applied to 100KGP.
From: ImmuneLENS characterizes systemic immune dysregulation in aging and cancer
The number of tumor samples per cancer histology is given above the plot. The panels represent snake plots for circulating and infiltrating TCRA T cell fractions and IGH B cell fractions, with each point representing a single blood or tumor sample. Above each IGH B cell fraction snake plot is a track, shown as a heatmap, displaying the proportion of different Ig B cells for each sample. Histology groups are arranged in ascending order based on the median circulating TCRA T cell fraction, and within each group, samples are sorted from lowest to highest value in each snake plot. Right, snake plots for the circulating T cell and B cell fractions within the 100KGP healthy cohort. No significant differences were identified (using ANOVA) in the proportions of B cell Ig status among cancer histology groups in either circulating or infiltrating samples. Horizontal red lines represent the median value per histology group. GI, gastrointestinal.
