Fig. 3: Genetic correlations (rG) between OCD and 112 phenotypes. | Nature Genetics

Fig. 3: Genetic correlations (rG) between OCD and 112 phenotypes.

From: Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Fig. 3

This includes psychiatric, substance use, cognition–socioeconomic status (SES), personality, psychological, neurological, autoimmune, cardiovascular (cardiovasc.), anthropomorphic–diet, fertility and other phenotypes. References and sample sizes of the corresponding summary statistics of the GWAS studies can be found in Supplementary Table 18. The OCD summary statistics are of the main meta-analysis (ncases = 53,660 and ncontrols = 2,044,417). Error bars represent the 95% confidence intervals for the genetic correlation estimates (rG). Red circles indicate significant associations with a P value adjusted for multiple testing with the Benjamini–Hochberg procedure to control the FDR (<0.05). Black circles indicate associations that are not significant. a., after; ADHD, attention-deficit hyperactivity disorder; ALS, amyotrophic lateral sclerosis; BMI, body mass index; embarras., embarrassment; freq, frequency; fr., from; HDL, high-density lipoprotein; IQ, intelligence quotient; LDL, low-density lipoprotein; neurot., neuroticism; nr., number; PTSD, post-traumatic stress disorder; sat., satisfaction; VN, verbal-numerical.

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