Extended Data Fig. 4: Functional and genomic characterization of DC/IC/NC enhancer classes in the mouse genome. | Nature Genetics

Extended Data Fig. 4: Functional and genomic characterization of DC/IC/NC enhancer classes in the mouse genome.

From: Conservation of regulatory elements with highly diverged sequences across large evolutionary distances

Extended Data Fig. 4

(a) Enrichment of promoter- and enhancer-specific histone modifications and ATAC-seq signal surrounding the distinct enhancer classes in mouse E10.5 heart samples. (b) Fraction of DC/IC/NC CREs overlapping one or multiple experimentally determined TFBSs (ReMap) vs. randomly selected genomic fragments. (c) Distance of enhancers to the nearest annotated TSS for DC/IC/NC enhancers (d) Fraction of enhancers located within annotated genes (and within genes overlapping exons or introns) as well as located in intergenic regions.

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