Extended Data Fig. 8: De novo development of different genetic alterations between paired primary and metastatic sites by cancer type. | Nature Genetics

Extended Data Fig. 8: De novo development of different genetic alterations between paired primary and metastatic sites by cancer type.

From: Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination

Extended Data Fig. 8: De novo development of different genetic alterations between paired primary and metastatic sites by cancer type.The alternative text for this image may have been generated using AI.

Percentage of patients with paired primary and metastatic samples demonstrating de novo mutations in antigen presenting mechanism (APM) genes, including B2M, TAP1, TAP2, HLA-A, HLA-B, and HLA-C. All samples were filtered to ensure a sample purity of greater than 20%.

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