Extended Data Fig. 1: Patient-derived and xenograft-derived CTC clusters.
From: Phylogenetic inference reveals clonal heterogeneity in circulating tumor cell clusters
a, Representative microscopic images of patient-derived CTC clusters stained for EpCAM, HER2 and EGFR (CTCs, green) and CD45 (white blood cells, magenta). Pseudo-coloring and gamma adjustments were applied to fluorescent images. Scale bar, 10 µm. b, Representative images of xenograft-derived CTC clusters preselection and postselection via robotic micromanipulation. The black arrow points to the targeted CTC cluster. Scale bar, 20 µm.
