We created a population-scale functional genomic dataset that maps whole blood regulatory variation in three South African groups. This resource supports the interpretation of genome-wide association studies in African-ancestry individuals, enabling translation to actionable discoveries.
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This is a summary of: Castel, S. E. et al. A map of blood regulatory variation in South Africans enables GWAS interpretation. Nat. Genet. https://doi.org/10.1038/s41588-025-02223-0 (2025).
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Empowering African GWAS with a map of blood regulatory variation. Nat Genet 57, 1574–1575 (2025). https://doi.org/10.1038/s41588-025-02228-9
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DOI: https://doi.org/10.1038/s41588-025-02228-9
