Extended Data Fig. 6: Colocalizations of GWASs in East Asian population and cis-eQTLs in OASIS.
From: Deciphering state-dependent immune features from multi-layer omics data at single-cell resolution
(a) Number of colocalizing eGenes shared among different autoimmune and blood-related traits. Bar plots indicating the number of genes in each set. eGenes colocalizing in only one trait are colored by pink, and those in multiple traits are connected by lines and colored by gray. (b) Colocalizations of GWAS variants in East Asian population and cis-eQTLs in OASIS for 6 traits with more than 10 colocalizations. Heatmap depicting PP.H4 from coloc75. Cell types of major cell type (L1) are colored by red. GWAS abbreviations: CD, Crohn’s disease; Hosp-COV, hospitalized COVID-19; HT, hyperthyroidism; IBD, inflammatory bowel diseases; LYM, lymphocyte count; MON, monocyte count; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; T1D, type 1 diabetes; UC, ulcerative colitis.
