Extended Data Fig. 4: Heatmap of gene expression by copy loss and/or DNA methylation. | Nature Genetics

Extended Data Fig. 4: Heatmap of gene expression by copy loss and/or DNA methylation.

From: DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution

Extended Data Fig. 4: Heatmap of gene expression by copy loss and/or DNA methylation.

TSG expression in samples with at least 2 tumor regions per category in LUAD (left) and LUSC (right). * indicates significance of the expression decrease relative to samples with no hypermethylation or copy number loss observed based on RRBS and WES analyses using a linear mixed model analysis. The colour scale (Z-score) is standardised by rows to allow comparisons within the same gene, with 0 being the mean value.

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