Extended Data Fig. 4: Comparison of PD-L1 expression on tumor cells and macrophages between progressors and non-progressors. | Nature Genetics

Extended Data Fig. 4: Comparison of PD-L1 expression on tumor cells and macrophages between progressors and non-progressors.

From: Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer

Extended Data Fig. 4: Comparison of PD-L1 expression on tumor cells and macrophages between progressors and non-progressors.The alternative text for this image may have been generated using AI.

(a) PD-L1 expression on tumor cells in the UQ cohort, comparing progressors and non-progressors. (b) PD-L1 expression on macrophages in the UQ cohort. (c) PD-L1 expression on tumor cells in the combined Yale + UQ cohorts. (d) PD-L1 expression on macrophages in the combined Yale + UQ cohorts. One-tailed t-tests were employed in cases where the direction of the effect was hypothesized a priori. The correlation between PD-L1 expression and (e) M1 macrophages, (f) M2 macrophages, (g) CD14+ myeloid cells and (h) panCK+ tumor cells within the TIME, are shown, assessed using Spearman’s rank correlation method.

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