Fig. 2: Cell-type and composition of tumor and stroma compartments. | Nature Genetics

Fig. 2: Cell-type and composition of tumor and stroma compartments.

From: Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer

Fig. 2: Cell-type and composition of tumor and stroma compartments.

a, A representative figure illustrates the different cell phenotypes in an ROI from a patient. b, The specific markers used in CODEX for identifying various cell types within the samples are listed. c, A representative tumor compartment from a highlights the cellular composition and diversity of cell types within the tumor. d, The variety of cell types present in the stromal compartment is shown. e, The proportions of different cell types within the tumor compartment of patients from the Yale cohort are grouped based on the 2-year PFS index, illustrating the potential relationship between cellular composition and patient prognosis. f, A similar analysis is presented for the tumor compartment of the UQ cohort, grouped by the 2-year PFS index. g, The distribution of different cell types within the stroma compartment of patients from the Yale cohort is grouped by the 2-year PFS index. h, Similarly, the proportions of different cell types within the stroma compartment of the UQ cohort are grouped by the 2-year PFS index, highlighting the diversity and potential prognostic implications of stromal cell composition.

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