Extended Data Fig. 8: Locityper runtime and memory usage.

Locityper runtime and memory usage at 10 randomly selected Illumina WGS datasets and 256 target loci, with bold lines showing average values. Standard reference panel (up to 90 haplotypes) was extended with randomly mutated haplotypes to measure the effect of growing pangenomes on Locityper runtime. Correspondingly, x-axis shows reference panel size, relative to the non-extended panel. Right y-axis shows runtime/peak memory, normalized by the average (total) value at the non-extended reference panel. a, Runtime was measured across three non-overlapping steps: read recruitment (green); read mapping to haplotypes (red); locus genotyping (blue). Total runtime is shown in yellow. b, Peak memory usage (Gb).