Extended Data Fig. 3: Scatterplot comparing heterozygote genotype counts of burden masks computed by REGENIE and estimated by REMETA.

Each row corresponds to a trait, and each column corresponds to an AAF bin for a burden test. Each panel includes burden masks computed across 7 annotation categories. For quantitative traits, heterozygote genotypes counts in the whole sample are displayed. For binary traits, heterozygote genotype counts in cases are displayed.