Table 1 Description of the cohorts used in this study

From: Genome-wide association analyses identify distinct genetic architectures for early-onset and late-onset depression

Country

Study

Cohort type

n MDD cases

n MDD controls

n eoMDD cases

n eoMDD controls

n loMDD cases

n loMDD controls

Denmark

iPSYCH2012

Case–cohort

20,804

23,854

18,429

23,854

NA

NA

iPSYCH2015

Case–cohort

10,487

15,772

8,105

15,772

NA

NA

Norway

MoBa

Population-based

9,573

89,849

882

7,683

NA

NA

Sweden

PREFECT, iCBT, STAGE, BASIC

Case–control

4,107

19,416

470

3,711

483

3,711

Estonia

EstBB

Population-based

49,950

100,660

8,791

35,742

14,656

29,593

Finland

FinnGen

Population-based

56,661

113,322

10,031

20,062

22,029

88,116

Total

  

151,582

362,873

46,708

106,824

37,168

121,420

UK (as comparison)

UKB

Population-based

25,162

431,658

3,402

226,627

9,084

226,627

  1. eoMDD (age at first MDD diagnosis ≤ 25 years). loMDD (age at first MDD diagnosis ≥ 50 years). The total sample sizes for the Nordic cohorts are shown in bold. EstBB, Estonian Biobank; iPSYCH, Integrative Psychiatric Research Consortium; MoBa, Norwegian Mother, Father and Child Cohort Study; UKB, UK Biobank.
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