Extended Data Fig. 5: Mouse models match corresponding human entities with statistical significance. | Nature Genetics

Extended Data Fig. 5: Mouse models match corresponding human entities with statistical significance.

From: Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models

Extended Data Fig. 5

a, Heatmap of the average distance of each mouse model to the different human entities. b, Oncoplot showing the predicted entity as well as the expected human entity to each mouse model. The matches in UMAP and random forest are statistically validated using a binomial test. c, Dotplot showing no correlation between matching success and distinctiveness of human entities in UMAP depictions. The color legend of Familiy, Class and Type in a) also applies to b) and c).

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