Supplementary Figure 4: Lack of IL-1 signaling does not affect viral control or immune cell infiltrates to the CNS.
From: Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1
a-c Plaque assay of CNS tissue from WNV-NS5-E218A infected wildtype (WT) and Il1r1 −/− animals at 6 d.p.i. d qPCR analysis of WNV envelope protein at 25 d.p.i. in hippocampus from WNV-NS5-E218A WT and Il1r1 −/− mice. e-l Flow cytometric analysis of stained single cell populations isolated from hippocampus of WT and Il1r1 −/− mice at 6 d.p.i. ns = not significant (P > 0.05 using two tailed student’s t test).
