Supplementary Figure 4: Estimation of the unique contributions of multiple baseline immunological parameters to the variation in stimulated cytokine production.
From: Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses
Adjusted R2 between a full and multiple-reduced multivariate linear models (MVLM) giving an estimation unique of the effect. Each colored bar represents how much additional variation (on top of the preceding colors) the MVLM for that category explains when conditioned on the other 9 MVLMs. The combined dataset consisted of 266 samples. Each sample represents an individual. Gene expression was not included in this analysis because of the relatively small sample size of the RNA-seq experiment after overlapping with the other datasets (n = 69). X-axis denotes adjusted R2 values. Y-axis denotes different cytokine-stimulation pairs.
