Supplementary Figure 2: CCR7^–CD38⁺CD4⁺ cells are enriched in Ki67⁺ accumulating during enteric fever.

(a) Expression of CCR7 and CD38 in the 20 distinct clusters identified by PhenoGraph analysis. (b) Proportion of PhenoGraph clusters within Ki67⁺ CD38⁺CCR7^- cells at the peak of Ki67⁺ cell accumulation. (c) Frequency of Ki67⁺ CD38⁺CCR7^- cells (Friedman Test p = 0.0130, Dunn’s Multiple Comparison Test D0 vs D4, D28, D90p = ns, D0 vs EF p = 0.0139) and of KI67 + cells non comprised within CD38⁺CCR7^- cells over time in challenged volunteers (n = 6) (Friedman Test p = 0.23, Dunn’s Multiple Comparison Test D0 vs D4, EF, D28, D90 p = ns). Box extends from the 25^th to the 75^th percentile and whiskers from the minimum to the maximum value; line indicates median.