Supplementary Figure 1: Characterization of Ki67+ cells accumulating during enteric fever.

(a)Gating strategy to identify CD4+ and CD4+Ki67+ cells in Mass Cytometry experiments. Frequency of Cluster 19 cells within Ki67+ (b) and total CD4+ T cells (c) at different time points after infection (n = 6). (b) Friedman Test p = 0.0147, Dunn’s Multiple Comparison Test D0 vs D4, D28, D90 p = ns, D0 vs EF p = 0.027. (c)Friedman Test p = 0.0159, Dunn’s Multiple Comparison Test D0 vs D4, D28, D90 p = ns, D0 vs EF p = 0.0247. (d) Total Ki67+ events (grey) and Cluster 19 events (red) across all samples were concatenated and expression of 20 markers against CD38 in the distinct populations is shown.