Supplementary Figure 9: Bcl11b-dependent Runx1 recruitment distinguishes the Tcrb and Tcrg genetic loci in primary pro-T cells.
From: Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16
The binding patterns of Runx1 and Bcl11b at the Tcrb locus (a) and Tcrg loci (b) in WT and Bcl11b KO DN3 cells are shown, with RNA-seq tracks below. Bcl11b-dependent Runx1 peaks are labeled with magenta rectangles. Data are representative of two independent experiments.
