Supplementary Figure 1: c-Myb-deficient CD8+ T cells display a more pronounced contraction.
From: The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity
(a,b) Flow cytometry of splenic CD8+ T cells (a) and percentage of pmel-1 T cells (b) in the lymph nodes (LN) after transfer of 105 pmel-1 Thy1.1 Mybfl/fl or pmel-1 Thy1.1 Myb∆/∆ CD8+ T cells into wild-type mice infected with gp100-VV, assessed 5d and 10d after infection (n = 3 mice per group). (c,d) Flow cytometry of splenic CD8+ T cells (c) and percentage (d) of pmel-1 T cells in the lung after transfer as described in a,b. Data are representative of two independent experiments. Data are shown after gating on live, CD8+ T cells (a, c). Data in b and d are shown as the mean ± s.e.m.; shapes represent individual mice. **= P < 0.01; ns, not significant (unpaired two-tailed Student’s t-test).
