Supplementary Figure 1: IFN-λ exhibits no immunostimulatory effect when antigen is applied by the intraperitoneal or subcutaneous route.
From: Interferon-λ enhances adaptive mucosal immunity by boosting release of thymic stromal lymphopoietin
a-b, Titers of HA-specific IgG subclasses on day 10 after the first and second booster immunization in sera of Mx1-WT mice immunized by the intraperitoneal (a) or subcutaneous (b) route with Influsplit Tetra® in the presence or absence of IFN-λ2. Data are representative of two independent experiments with n=6 (a) and n=7 (b) animals per group. Error bars represent SEM centered on the mean. Each symbol represents an individual animal. c-d, Titers of M2e-specific IgG subclasses on day 10 post booster immunization in sera of Mx1-WT mice immunized by either the intraperitoneal (c) or subcutaneous (d) route with M2e vaccine in the presence or absence of IFN-λ2. Data are representative of two independent experiments with n=6 animals per group. Error bars represent SEM centered on the mean. Each symbol represents an individual animal.
