Supplementary Figure 2: IFN-λ signaling is not required for development of antibody responses in bronchoalveolar lavage fluid following IAV. | Nature Immunology

Supplementary Figure 2: IFN-λ signaling is not required for development of antibody responses in bronchoalveolar lavage fluid following IAV.

From: Interferon-λ modulates dendritic cells to facilitate T cell immunity during infection with influenza A virus

Supplementary Figure 2: IFN-λ signaling is not required for development of antibody responses in bronchoalveolar lavage fluid following IAV.The alternative text for this image may have been generated using AI.

WT and Ifnlr1−/− mice were mock- or IAV-infected with PBS or 40 PFU PR8. Bronchoalveolar lavage fluid was harvested on D35 post infection, and IAV-specific IgM, IgG, IgG1, IgG2a, and IgA antibody levels were determined by ELISA. n=2 (mock) or 4 (IAV) mice/group. Error bars show mean ± SD. Significance was determined using one-way ANOVA followed by Tukey’s multiple comparisons test between WT IAV and Ifnlr1−/− IAV. n.s. indicates p=0.0504, * indicates p<0.05, ** indicates p<0.0001.

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