Table 1 Standard B cell definitions
From: Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19
B cell type | Primary population | Secondary populations |
|---|---|---|
Transitional | Tr: CD19+ CD27− CD38int CD24+ | CD21lo Tr: CD24hi CD21− |
CD21hi Tr: CD24lo CD21+ | ||
Naive | N: CD19+ CD27− CD38− CD24− IgD+ | aN: CD11c+ |
rN: CD11c− | ||
Double negative | DN: CD19+ CD27 − CD38− CD24− IgD− | DN1: CD11c− CD21+ |
DN2: CD11c+ CD21− | ||
DN3: CD11c− CD21− | ||
Memory | M: CD19+ CD27+ CD38−/lo | mM: IgM+ IgD− |
dM: IgM− IgD+ | ||
usM: IgM+ IgD+ | ||
sM: IgM− IgD− | ||
ASCs | ASC: CD19+ CD27+ CD38hi | CD138neg ASC: CD138− |
CD138pos ASC: CD138+ |
