Extended Data Fig. 3: Different clustering approaches and signatures do not parse out the data into TH subsets. | Nature Immunology

Extended Data Fig. 3: Different clustering approaches and signatures do not parse out the data into TH subsets.

From: Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes

Extended Data Fig. 3: Different clustering approaches and signatures do not parse out the data into TH subsets.

a, KNN clusters shown on hash-tagged tSNE. Percentages of cells corresponding to each signature in each KNN cluster are shown in the table. b, Biscuit clusters shown on hash-tagged tSNE. Percentages of cells corresponding to each signature in each Biscuit cluster are shown in the table. c, Backspin clusters shown on hash-tagged tSNE. Percentages of cells corresponding to each signature in each Backspin cluster are shown in the table. d, Overlay of pathogenic TH17 signatures from refs. 22,23. Left panel: all Teff; right panel: only Il17a+ Teff. e, Overlay of Citrobacter TH17 signature from ref. 24 on the tSNE plot.

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