Extended Data Fig. 5: Memory_associated_gene_loci_are_accessible_in_the_CD94+CD56hiNK_cells. | Nature Immunology

Extended Data Fig. 5: Memory_associated_gene_loci_are_accessible_in_the_CD94+CD56hiNK_cells.

From: HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

Extended Data Fig. 5: Memory_associated_gene_loci_are_accessible_in_the_CD94+CD56hiNK_cells.

a, H3K4me1 and H3K4me3 CUT&RUN and ATAC-Seq signal on genes associated with memory T and NK cells, except for effector marker KLRG1, on the indicated NK cell subsets. b, IFN-γ production among CD56dim and CD56hiNK cells after stimulation with IL-12 + IL-15 for 16 hr (n = 4). mean ± s.e.m.; two tailed paired t-test, *p < 0.01. c, H3K4me1 and H3K4me3 CUT&RUN and ATAC-Seq signal at loci for IFN-γ signaling related genes. Data are from HIV-1– blood donors.

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