Extended Data Fig. 2: Analysis of hallmark transcription factors. | Nature Immunology

Extended Data Fig. 2: Analysis of hallmark transcription factors.

From: Dynamics in protein translation sustaining T cell preparedness

Extended Data Fig. 2

(a) Frequency of ATAC-Seq peaks annotated to different genomic regions. (b) Frequency of ETS1 ChIP-Seq peaks annotated to different genomic regions. (c) Examples of activation markers that were up-regulated in TILs (CD69 and PD1) and proteins that were downregulated (KLF2, CD62L, and FAM65B). n = 1627 for T cells from blood, n = 2170 for T cells from tumors. Violin plot width is based on a Gaussian kernel density estimate of the data (estimated by the density function with standard parameters), scaled to have maximum width = 1. Data are from Zheng et al. 2016.

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