Extended Data Fig. 3: Topical Neosporin ointment treatment efficiently reduces commensal bacteria in murine skin.
From: The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
a, Photographs of a blood-agar plate showing bacterial colonies grown overnight from skin samples harvested from five different vehicle-treated and Neosporin-treated mice (left). The number of colony forming units (CFU) in each group was then calculated (right). Data represent the mean + s.e.m. n = 5. *P<0.01, **P<0.001 (one-way ANOVA followed by Tukey’s multiple comparisons test). b, Quantification of bacterial 16S rDNA by qPCR in the skin of vehicle-treated, Neosporin-treated, or Neosporin-treated Staphylococcus epidermidis-recolonized SPF-housed mice, and untreated or Staphylococcus epidermidis-recolonized germ-free (GF) mice.
