Extended Data Fig. 10: Riok2 haploinsufficiency recapitulates del(5q) MDS transcriptional changes.
From: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias
a,b, GSEA enrichment plots comparing proteins up-regulated (a) and down-regulated (b) upon Riok2 haploinsufficiency to the transcriptional changes seen in del(5q) MDS. c, Schematic of mechanism underlying Riok2 haploinsufficiency-induced, IL-22 –induced anemia.
