Extended Data Fig. 7
a–d, Colony forming units (CFU)-based assay determining the overgrowth of C albicans 1 day (left panel) and 14 days (right panel) after the oral colonization. The tissues were isolated from Aire whole-body knockout mice (Aire−/−), their wild-type littermates (Aire+/+), Rorc-Cre– Airefl/fl (WT) and Rorc-Cre+Airefl/fl (ILC3ΔAire) mice. CFU was determined by plating the lysates obtained from the kidney (a), oral cavity (b), esophagus (c), small intestine (d) (n = 6, mean ± SD, two-tailed Student’s t-test). P-value indicators: *** = P-value < 0.0001, ** = P-value < 0.001, * = P-value < 0.05, ns = not significant.
