Extended Data Fig. 6: Repertoire analysis pipeline and B cell sorting. | Nature Immunology

Extended Data Fig. 6: Repertoire analysis pipeline and B cell sorting.

From: Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet+ B cells

Extended Data Fig. 6

(a) Repertoire analysis pipeline. See Methods for details. (b) Gating and sort purity of batch sorted CD38int, CD38− and CD27+ B cells. Gating is shown for a HC-Ag and a pRD-Ag subject analyzed parallel in the same experiment, and are representative of six independent experiment, HC-Ag (n = 6), pRD-Ag (n = 5) and pRD-N (n = 1).

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