Extended Data Fig. 7: Bcl-xL rescue of CD40 deficiency in cDC1.
From: Mechanisms of CD40-dependent cDC1 licensing beyond costimulation
a, Flt3L-treated BM cultures from Cd40-/- mice were transduced with Bcl-xL, and cDC1s were sorted on day 10 of culture. Representative FACS plots depicting the full gating strategy (top) and the post-sort analysis for Bcl-xL-GFP+ expressing cDC1s (middle)and untransduced Bcl-xL-GFP− cDC1s (bottom) and. b, Flt3L-treated BM cultures from Cd40-/- mice were transduced with EV, and cDC1s were sorted on day 10 of culture. Representative FACS plots depicting the full gating strategy (top) and the post-sort analysis for EV-GFP+ expressing cDC1s (middle) and untransduced EV-GFP− cDC1s (bottom).
