Extended Data Fig. 5: Properties of ASAPseq library during chronic infection. | Nature Immunology

Extended Data Fig. 5: Properties of ASAPseq library during chronic infection.

From: Profound phenotypic and epigenetic heterogeneity of the HIV-1-infected CD4+ T cell reservoir

Extended Data Fig. 5: Properties of ASAPseq library during chronic infection.

(A) UpSet plot of unique cell barcodes that were collected from each modality (ATAC versus ADT) and detection of proviral reads (HIV) separated by individual. (B) (top) Sequenced regions that are aligned by bwa mem to the proviral genome (HXB2) and recovered by hiv-haystack. Each row is a cell and each column is a base pair spanning the proviral genome. Refer to Extended Data Fig. 1 legend for more detailed information. (C) UMAP representation of the ATAC component with numeric labeling prior to manual annotation.

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