Extended Data Fig. 3: Differential expression of select antigens for in vitro model.
From: Profound phenotypic and epigenetic heterogeneity of the HIV-1-infected CD4+ T cell reservoir
Differential expression of surface antigens was assessed (DESeq2 method in Seurat; two-sided with multiple comparison adjustment using Bonferroni-Hochberg method) to compare between HIV- or HIV + cells in specific cell groupings: (A) all CD4 + T-cells (n = 1279 cells for HIV + and n = 5315 cells for HIV-) and (B) early differentiated CD4 + T-cells (n = 216 cells for HIV + and n = 3958 cells for HIV-). Markers are ranked in (A-B) by π-score (see Fig. 1E legend). All markers shown have an adjusted p-value < 0.05.
