Extended Data Fig. 2: CD40 stimulation induces successive waves of transcriptional regulation in IFN-αA-conditioned BMDC1.
From: CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity
a, Genes included in modules 1, 2 and 3 from the co-expression analysis (Fig. 2e) displayed as heatmap. b, Top GO-terms associated with the genes included in modules 1, 2 and 3 (Fig. 2e). c, Representative immunoblotting of IκBα degradation and P65 phosphorylation in 'BMDC1-IFNαA+CD40-15min', 'BMDC1-IFNαA-30min' and ‘BMDC1-IFN-αA+CD40-4h’ compared to ‘BMDC1-IFN-αA’, ‘BMDC1-CD40’ and ‘BMDC1-unstimulated’. Full gels of the two independent experiments are displayed below. Probing of β-actin and/or total P65 served as loading control.
