Extended Data Fig. 5: Assessment of total anti-OVA IgG in sera 3 weeks following a prime-boost schedule.
From: mRNA vaccine against malaria tailored for liver-resident memory T cells
Male B6 mice were vaccinated with mOVA vaccine alone (containing 5 µg mRNA), or mOVA adjuvanted with αGC or αGCB, on days 0 and 21, with sera collected 3 weeks after the boost analysed for total anti-OVA IgG by ELISA. Two independent experiments were combined to give 10 mice per group with the exception of the αGC group which contains 11 mice. Geometric mean ± 95 % confidence intervals for EC50 values are shown. Data were log-transformed and compared by one-way ANOVA with Tukey’s multiple comparison post-test. ****P < 0.0001.
