Extended Data Fig. 7: Transcriptional regulation of TCR- and cytokine-stimulated MAIT cells exhibits shared and distinct properties.
From: Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
a,b, Violin plots showing the activity (AUCell scores) of selected TCR-specific (a) and cytokine-specific (b) transcription factor regulons in unstimulated, TCR-stimulated and cytokine-stimulated MAIT cells. n = 3 donors. Differential activity analysis was performed for all pairwise comparisons using MAST. Bonferroni adjusted P values are shown (nonsignificant results omitted). ****P < 0.0001. c, Over-representation analysis on predicted T-bet (TBX21) target genes. Significant Reactome pathways and associated Benjamini-Hochberg adjusted P values are shown.
