Extended Data Fig. 3: Immune responses to C.albicans isolates from COVID-19 patients. | Nature Immunology

Extended Data Fig. 3: Immune responses to C.albicans isolates from COVID-19 patients.

From: Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19

Extended Data Fig. 3: Immune responses to C.albicans isolates from COVID-19 patients.The alternative text for this image may have been generated using AI.

a, Representative graphs depicting the flow cytometry gating strategy for defining murine neutrophil populations in tissues. b-d, Anti-C. albicans specific IgG titers (b), the amount of neutrophils in peripheral blood (c) and lung (d) in antibiotic-treated mice orally gavaged or not (PBS, n = 7) with either C. glabrata (CgCOV3, n = 7) or C. albicans (CaCOV1, CaCOV5, CaCOV2, n = 7) isolated from COVID-19 patient’s stool. Immune responses were assessed at 2 weeks after colonization. In boxplots in b, the center is drawn through the median of the measurement, and the lower and upper bounds of the box correspond to the first and third quartile. The whiskers go down to the smallest value and up to the largest. The bar graphs in c and d presented as mean ± SEM. The results were pooled from two experiments. P values were calculated using the one-way ANOVA followed by Tukey’s multiple comparison. ns = not significant. Related to Figs. 2 and 3.

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