Extended Data Fig. 5: Comparative gene expression profile induced by BBγ/BBδ and BBζ/BBε upon antigen stimulation. | Nature Immunology

Extended Data Fig. 5: Comparative gene expression profile induced by BBγ/BBδ and BBζ/BBε upon antigen stimulation.

From: Harnessing CD3 diversity to optimize CAR T cells

Extended Data Fig. 5: Comparative gene expression profile induced by BBγ/BBδ and BBζ/BBε upon antigen stimulation.The alternative text for this image may have been generated using AI.

a, Pathway analysis (GO and Consensus) directly comparing BBγ with BBδ (genes in the UP graph are significantly up-regulated in BBγ and genes in the DOWN graph are significantly up-regulated in BBδ). b, Pathway analysis (Reactome and Consensus) directly comparing BBζ with BBε (genes in the UP graph are significantly up-regulated in BBζ and genes in the DOWN graph are significantly up-regulated in BBε). Two-sample t-test, the dashed vertical line indicates statistical significance, p < 0.05. Relevant pathways are bolded. n = 3 independent donors.

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