Extended Data Fig. 5: Comparative gene expression profile induced by BBγ/BBδ and BBζ/BBε upon antigen stimulation. | Nature Immunology

Extended Data Fig. 5: Comparative gene expression profile induced by BBγ/BBδ and BBζ/BBε upon antigen stimulation.

From: Harnessing CD3 diversity to optimize CAR T cells

Extended Data Fig. 5

a, Pathway analysis (GO and Consensus) directly comparing BBγ with BBδ (genes in the UP graph are significantly up-regulated in BBγ and genes in the DOWN graph are significantly up-regulated in BBδ). b, Pathway analysis (Reactome and Consensus) directly comparing BBζ with BBε (genes in the UP graph are significantly up-regulated in BBζ and genes in the DOWN graph are significantly up-regulated in BBε). Two-sample t-test, the dashed vertical line indicates statistical significance, p < 0.05. Relevant pathways are bolded. n = 3 independent donors.

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