Extended Data Fig. 1: Small pre-B cells have a unique developmental signature.
From: BRWD1 orchestrates small pre-B cell chromatin topology by converting static to dynamic cohesin
a, Total and overlapping accessibility peaks (ATAC-seq) in WT pro-B, WT large pre-B, WT small pre-B, WT Immature B, Brwd1-/- small pre-B and Rag1-/-B18i (Igμ) small pre-B cells. b, Differential heatmap showing the up and down-regulated genes in WT small pre-B cells compared to Rag1-/-B18i (Igμ) small pre-B cells. c, HiC interaction matrices along with TAD scores in indicated cell populations for genomic regions containing T cell lineage specific (Bcl11b), B cell lineage specific (Ebf1) and granulocyte lineage specific (Il1f9) genes.
