Extended Data Fig. 1: Identification of an inflammatory MmSC subtype after acute skeletal-muscle injury. | Nature Immunology

Extended Data Fig. 1: Identification of an inflammatory MmSC subtype after acute skeletal-muscle injury.

From: A discrete ‘early-responder’ stromal-cell subtype orchestrates immunocyte recruitment to injured tissue

Extended Data Fig. 1

a, Gating strategy for the cytofluorimetric sorting of MmSCs from hindlimb muscles. b, Heat map of the top 20 differentially expressed genes in MmSCs from D1 following CTX-induced injury comparing each cluster vis-à-vis all other clusters. c, Violin plot of the expression of the early signature (top 100 transcripts distinguishing early time points from the rest) across all MmSCs clusters on D1 following CTX-induced injury. d, Density plot of the expression of the indicated genes and gene signatures in MmSCs from D1 following CTX-induced injury. e, Violin plots of the expression of the signatures differentiating the four muscle stromal subtypes from Scott et al.44 across all MmSCs clusters on D1 following CTX-induced injury.

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